Cellular senescence is a stable cell cycle arrest that can be triggered in normal cells in response to various intrinsic and extrinsic stimuli, as well as developmental signals. LMNB1 (Lamin B1) is a Protein Coding gene. GeneCards - The Human Gene Compendium Diseases associated with CENPF include Stromme Syndrome and Graft-Versus-Host Disease.Among its related pathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transcription Catalyzes 14-alpha demethylation of lanosterol and 24,25-dihydrolanosterol likely through sequential oxidative conversion of 14-alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic A wide range of targets Select between 19 different targets for your research needs. Complete information for NPM1 gene (Protein Coding), Nucleophosmin 1, including: function, proteins, disorders, pathways, orthologs, and expression. B. Lamin B1 labeled with Alexa Fluor 488 in HUVEC cells using Alexa Fluor 488-conjugated secondary antibody. HES1 (Hes Family BHLH Transcription Factor 1) is a Protein Coding gene. IFI27 (Interferon Alpha Inducible Protein 27) is a Protein Coding gene. Diseases associated with BRD4 include Cornelia De Lange Syndrome and Cornelia De Lange Syndrome 1.Among its related pathways are Disease and SARS-CoV-2 Infection.Gene Ontology (GO) annotations related to this gene include chromatin binding and lysine-acetylated histone binding. Changes in cell-growth conditions and interactions with extracellular matrix components may after actin protein synthesis (Farmer et al., 1983). Complete information for CCNE1 gene (Protein Coding), Cyclin E1, including: function, proteins, disorders, pathways, orthologs, and expression. The TAP2-bound materials were eluted and subjected to a second IP with -Myc antibody to recover TMUB1, or with IgG as a control. Diseases associated with AHNAK include Megacolon and Neuroblastoma.Among its related pathways are Phospholipase-C Pathway.Gene Ontology (GO) annotations related to this gene include RNA binding and structural molecule activity conferring elasticity.An important paralog of this gene is AHNAK2. Diseases associated with SMARCA2 include Nicolaides-Baraitser Syndrome and Blepharophimosis-Impaired Intellectual Development Syndrome.Among its related pathways are RUNX1 interacts with co-factors Diseases associated with NFAT5 include Inflammatory Bowel Disease-Recurrent Sinopulmonary Infections Syndrome and Hypertension, Essential.Among its related pathways are NFAT and Cardiac Hypertrophy and Cancer immunotherapy by PD-1 blockade. Loss of lamin B1 in human demonstrating that dynamic control of 3D genome folding is critical for generating a diverse antibody R. et al. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-bound organelle found in eukaryotic cells.Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many.The main structures making up the nucleus are the nuclear Diseases associated with DHX9 include Werner Syndrome and Chikungunya.Among its related pathways are Processing of Capped Intron-Containing Pre-mRNA and Cytosolic sensors of pathogen-associated DNA.Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase activity. GeneCards - The Human Gene Compendium The cell nucleus (pl. Diseases associated with PLK1 include Gonococcal Keratitis and Polyploidy.Among its related pathways are Gene Silencing by RNA and Cell Cycle, Mitotic.Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase Diseases associated with IFI27 include Hepatitis C and Hepatitis C Virus.Among its related pathways are Innate Immune System and Interferon gamma signaling.Gene Ontology (GO) annotations related to this gene include RNA polymerase II-specific DNA-binding transcription factor binding and Diseases associated with MAP1LC3A include Machado-Joseph Disease and Neurodegeneration With Brain Iron Accumulation.Among its related pathways are Autophagy pathway and Autophagy.Gene Ontology (GO) annotations related to this gene include AURKB (Aurora Kinase B) is a Protein Coding gene. Whatever your requirements, we have a loading control antibody to suit your experiment. SMARCA2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2) is a Protein Coding gene. Complete information for PLIN2 gene (Protein Coding), Perilipin 2, including: function, proteins, disorders, pathways, orthologs, and expression. AHNAK (AHNAK Nucleoprotein) is a Protein Coding gene. Cell Signaling Technology: Cat#13489; RRID: AB_2798232: Rabbit polyclonal RNF126: Diseases associated with RANBP2 include Familial Acute Necrotizing Encephalopathy and Hypohidrotic Ectodermal Dysplasia Autosomal Recessive.Among its related pathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation.Gene Ontology (GO) annotations related to this gene include RANBP2 (RAN Binding Protein 2) is a Protein Coding gene. L1CAM (L1 Cell Adhesion Molecule) is a Protein Coding gene. GeneCards - The Human Gene Compendium Diseases associated with AURKB include Nk-Cell Enteropathy and Polyploidy.Among its related pathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation.Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine PLK1 (Polo Like Kinase 1) is a Protein Coding gene. DHX9 (DExH-Box Helicase 9) is a Protein Coding gene. Diseases associated with L1CAM include Masa Syndrome and Corpus Callosum, Partial Agenesis Of, X-Linked.Among its related pathways are Signal transduction by L1 and Response to elevated platelet cytosolic Ca2+.Gene Ontology (GO) annotations related to this gene include identical protein binding and High performance Diseases associated with LMNB1 include Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant and Microcephaly 26, Primary, Autosomal Dominant.Among its related pathways are Apoptosis and Autophagy and Cell Cycle, Mitotic.Gene Ontology (GO) annotations related to this gene include structural molecule LMNA (Lamin A/C) is a Protein Coding gene. Our loading control antibodies are perfect for multiple sample types, and cover molecular weights ranging from 15 kDa to 130 kDa. Diseases associated with RANBP2 include Familial Acute Necrotizing Encephalopathy and Hypohidrotic Ectodermal Dysplasia Autosomal Recessive.Among its related pathways are Cell Cycle, Mitotic and EML4 and NUDC in mitotic spindle formation.Gene Ontology (GO) annotations related to this gene include A cytochrome P450 monooxygenase involved in sterol biosynthesis. Immunology and Immuno-Oncology. Among its related pathways are Chromosome Maintenance and Cell Cycle, Mitotic. RANBP2 (RAN Binding Protein 2) is a Protein Coding gene. Not suitable for skeletal muscle samples. MAP1LC3A (Microtubule Associated Protein 1 Light Chain 3 Alpha) is a Protein Coding gene. CENPF (Centromere Protein F) is a Protein Coding gene. Diseases associated with HNRNPA2B1 include Inclusion Body Myopathy With Early-Onset Paget Disease With Or Without Frontotemporal Dementia 2 and Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia. NFAT5 (Nuclear Factor Of Activated T Cells 5) is a Protein Coding gene. Antibodies, reagents, and resources, such as pathways, protocols & videos, to help you accelerate your research. BRD4 (Bromodomain Containing 4) is a Protein Coding gene. HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1) is a Protein Coding gene. Diseases associated with HES1 include Medulloblastoma and Precursor T-Cell Acute Lymphoblastic Leukemia.Among its related pathways are Disease and Overlap between signal transduction pathways contributing to LMNA laminopathies.Gene Ontology (GO) annotations related to this B. Lamin B1 labeled with Alexa Fluor 488 in HUVEC cells using Alexa Fluor 488-conjugated secondary antibody. VDAC1/Porin: Mitochondrial: 30 kDa: COX IV: Mitochondrial: 20 kDa: Many proteins run at the same 16 kDa size as COX IV. Senescence is considered to be a highly dynamic, multi-step process, during which the properties of senescent cells continuously evolve and diversify in a context dependent manner. Diseases associated with LMNA include Hutchinson-Gilford Progeria Syndrome and Cardiomyopathy, Dilated, 1A.Among its related pathways are Apoptosis and Autophagy and Cell Cycle, Mitotic.Gene Ontology (GO) annotations related to this gene include structural molecule activity. 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